Polymer porous material ndi zinthu za polima zomwe zimakhala ndi ma pores ambiri opangidwa ndi mpweya womwazika muzinthu za polima.
Kapangidwe kameneka kabwino kwambiri pakugwiritsa ntchito zida zotulutsa mawu, kulekanitsa ndi kutsatsa, kumasulidwa kwamankhwala, scaffold fupa ndi zina.
Zida zamakono za porous, monga polypropylene ndi polyurethane, sizili zophweka kuti ziwonongeke ndikutenga mafuta ngati zipangizo, zomwe zidzawononge chilengedwe.
Chifukwa chake, anthu adayamba kuphunzira zinthu zomwe zimatha kuwonongeka ndi bowo.
Kugwiritsa ntchito PLA potsegula dzenje:
PLA zotsegula dzenje zilinso ndi zovuta zina, zomwe zimalepheretsa kugwiritsa ntchito kwake pazinthu zopanda dzenje, monga:
1. Maonekedwe a khirisipi, mphamvu zochepa zochepetsera komanso kusowa kwa elasticity ya perforated material.
2. Pang'onopang'ono kudzitsitsa.
Ngati atasiyidwa m'thupi kwa nthawi yayitali ngati mankhwala, angayambitse kutupa.
3. Kukhetsa.
Kugwirizana kochepa kwa maselo, ngati atapangidwa kukhala mafupa opangira kapena ma cell a scaffold ndizovuta kumamatira ndikuchulukana.
Pofuna kukonza zolakwika za PLA zotsegula dzenje, kusakaniza, kudzaza, copolymerization ndi njira zina zinagwiritsidwa ntchito pofuna kukonza zipangizo za PLA zotsegula.
Nawa njira zingapo zosinthira za PLA:
1.PLA/PCL kuphatikiza kusinthidwa
PCL, kapena polycaprolactone, ndi zinthu zomwe zimatha kuwonongeka ndi biocompatibility, kulimba komanso kulimba kwamphamvu.
Kuphatikiza ndi PLA kumatha kupititsa patsogolo kulimba kwamphamvu kwa PLA.
Ofufuzawo adapeza kuti katunduyo amatha kuwongoleredwa ndikuwongolera chiŵerengero cha PCL ndi PLA. Pamene chiŵerengero cha misa cha PLA ku PCL chinali 7: 3, mphamvu zowonongeka ndi modulus zazinthuzo zinali zapamwamba.
Komabe, kulimba kumachepa ndi kuchuluka kwa pore diameter.
Zinthu za PLA/PCL sizowopsa ndipo zimatha kugwiritsidwa ntchito m'minofu yaying'ono yam'mimba.
2.PLA/PBAT kuphatikiza kusinthidwa
PBAT ndi zinthu zowonongeka, zomwe zimakhala ndi kuwonongeka kwa polyester ya aliphatic komanso kulimba kwa poliyesitala wonunkhira. Kuwonongeka kwa PLA kumatha kupitsidwanso mutaphatikizana ndi PLA.
Kafukufukuyu akuwonetsa kuti pakuwonjezeka kwa zinthu za PBAT, porosity ya zinthu zotseguka-bowo imachepa (porosity ndipamwamba kwambiri pamene PBAT zili ndi 20%), ndipo kuphulika kwa fracture kumawonjezeka.
Chosangalatsa ndichakuti, ngakhale kuwonjezera kwa PBAT kumachepetsa kulimba kwa PLA, kulimba kwamphamvu kwa PLA kumakulirakulirabe ikasinthidwa kukhala zinthu zosatsegula.
3.PLA/PBS kuphatikiza kusinthidwa
PBS ndi zinthu zomwe zimatha kuwonongeka, zomwe zimakhala ndi makina abwino, kukana kutentha kwambiri, kusinthasintha komanso kutha kukonza, ndipo ili pafupi kwambiri ndi PP ndi ABS.
Kuphatikiza PBS ndi PLA kumatha kupangitsa kuti PLA ikhale yolimba komanso yosinthika.
Malingana ndi kafukufuku, pamene chiwerengero cha PLA: PBS chinali 8: 2, zotsatira zake zinali zabwino kwambiri; ngati PBS idawonjezedwa mopitilira muyeso, porosity yazinthu zotseguka zikadachepetsedwa.
4.PLA/BIOactive galasi (BG) kudzaza kusinthidwa
Monga bioactive galasi zakuthupi, BG makamaka wapangidwa pakachitsulo sodium calcium phosphorous okusayidi, amene akhoza kusintha makina katundu ndi bioactivity wa PLA.
Ndi kuchuluka kwa zomwe zili mu BG, machulukidwe azinthu zotseguka amachulukira, koma kulimba kwamphamvu komanso kutalika kwanthawi yopuma kunachepa.
Pamene BG zili 10%, porosity wa zinthu otsegula dzenje ndi apamwamba (87.3%).
Zolemba za BG zikafika 20%, mphamvu yopondereza ya kompositi ndiyokwera kwambiri.
Kuphatikiza apo, zinthu zophatikizika za PLA/BG zimatha kuyika osteoid apatite wosanjikiza pamwamba komanso mkati mwamadzi am'thupi, omwe angapangitse kusinthika kwa mafupa. Chifukwa chake, PLA/BG ili ndi kuthekera kogwiritsidwa ntchito m'mafupa.
Nthawi yotumiza: 14-01-22